Category: Procaine penicillin

Procaine penicillin

23.10.2020 By Nakasa

If you are a consumer or patient please visit this version. Inactive Ingredients: Methylparaben 1. ACTIONS : Penicillin G is an effective bactericide in the treatment of infections caused primarily by penicillin-sensitive organisms, such as Streptococcus equi and Erysipelothrix rhusiopathiaeas well as the gram negative organism Pasteurella multocida.

Cattle and sheep - bacterial pneumonia shipping fever caused by Pasteurella multocida.

Do not inject subcutaneously, into a blood vessel, or near a major nerve. Use a 16 or 18 gauge needle, 1. The needle and syringe should be washed thoroughly before use.

The needle and syringe should then be sterilized by placing in boiling water for 15 to 20 minutes. No vial should be entered more than 15 times with a 16 gauge needle or more than 40 times with an 18 gauge needle. The product should then be administered by using the following procedure:. After filling the syringe, make sure the needle is empty by pulling back the plunger of the syringe until a small air bubble appears.

Then detach the needle from syringe. Insert the needle deep into the muscle, attach the syringe and withdraw the plunger slightly. If blood appears, withdraw the needle and insert it into a different location. Daily treatment should be continued for at least 48 hours after temperature has returned to normal and all other signs of infection have subsided. Animals treated with Penicillin G Procaine Injectable Suspension Alternate Method should show noticeable improvement within 36 to 48 hours.

procaine penicillin

Treatment should not exceed 7 days in non-lactating dairy and beef cattle, sheep, and swine, or 5 days in lactating dairy cattle. If no improvement is observed within 48 hours, consult your veterinarian. Milk that has been taken from animals during treatment and for 48 hours after the last treatment must not be used for food. The daily treatment schedule should not exceed seven 7 days of treatment in non-lactating dairy and beef cattle, sheep and swine, or five 5 days in lactating dairy cattle.

The drug should be discontinued for the following time periods before treated animals are slaughtered for food: Cattle - 4 days; Sheep - 8 days; Swine - 6 days; non-ruminating calves - 7 days. If such signs of sensitivity occur, stop medication and call your veterinarian. In some instances, particularly if respiratory distress is severe, immediate injection of epinephrine or antihistamine may be necessary. As with any antibiotic preparation, prolonged use may result in overgrowth of non-susceptible organisms, including fungi.

If this condition is suspected, stop medication and consult your veterinarian. DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed. DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use.

Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImagewe no longer display the RxImage pill images associated with drug labels. We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels.Penicillin G procaine injection is used to treat certain infections caused by bacteria.

Penicillin G procaine injection should not be used to treat gonorrhea a sexually transmitted disease or early in the treatment of certain serious infections.

Penicillin G procaine injection is in a class of medications called penicillins. It works by killing bacteria that cause infections. Antibiotics such as penicillin G procaine injection will not work for colds, flu, or other viral infections.

Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment. Penicillin G procaine injection comes as a suspension liquid in a prefilled syringe to inject into the muscles of the buttocks or thigh by a doctor or nurse in a medical facility. It is usually given once a day.

procaine penicillin

The length of your treatment depends on the type of infection that you have and how well you respond to the medication. You should begin to feel better during the first few days of treatment with penicillin G procaine injection.

If your symptoms do not improve or get worse, call your doctor. Be sure to keep all appointments to receive penicillin G procaine injection on schedule even if you feel better. If you stop receiving penicillin G procaine injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

You may experience a sudden severe reaction immediately after receiving a dose of penicillin G procaine injection that may last for approximately 15 to 30 minutes. Tell your doctor if you experience any of the following symptoms right after your injection: anxiety, confusion, agitation, depression, weakness, seizures, seeing things or hearing voices that do not exist, aggressive behavior, and fear of dying.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. If you miss an appointment to receive penicillin G procaine injection, call your doctor as soon as possible.

Penicillin G procaine injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Keep all appointments with your doctor and the laboratory.

Your doctor will order certain lab tests to check your body's response to penicillin G procaine injection. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.

It is also important information to carry with you in case of emergencies. Generic alternatives may be available. Penicillin G Procaine Injection pronounced as pen" i sil' in g proe' kane. Why is this medication prescribed?

procaine penicillin

How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow?Procaine benzylpenicillin also known as penicillin G procaineis an antibiotic useful for the treatment of a number of bacterial infections.

Side effects include pain at the site of injection, blood clotting problemsseizuresand allergic reactions including anaphylaxis. Procaine benzylpenicillin was introduced for medical use in Specific indications for procaine penicillin include: [7]. At high doses procaine penicillin can cause seizures and CNS abnormalities due to procaine present in it. It is a form of penicillin which is a combination of benzylpenicillin and the local anaesthetic agent procaine. From Wikipedia, the free encyclopedia.

Further information: Penicillin drug reaction. World Health Organization. Archived PDF from the original on 13 December Retrieved 8 December Archived from the original on 20 December Retrieved 10 December CRC Press.

Archived from the original on World Health Organization model list of essential medicines: 21st list Geneva: World Health Organization. International Drug Price Indicator Guide. Australian Medicines Handbook. Adelaide: Australian Medicines Handbook. MMWR Morb. Last accessed June 18, Archived from the original PDF on 11 April Retrieved 26 March Medically reviewed by Drugs. Last updated on Nov 1, To reduce the development of drug-resistant bacteria and maintain the effectiveness of Penicillin G Procaine and other antibacterial drugs, Penicillin G Procaine should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

This product is designed to provide a stable aqueous suspension of Penicillin G Procaine, ready for immediate use. This eliminates the necessity for addition of any diluent, required for the usual dry formulation of injectable penicillin.

Penicillin G Procaine is chemically designated as 2 S5 R6 R -3,3-Dimethyloxo 2-phenylacetamido thiaazabicyclo[3. Its structural formula is as follows:. Penicillin G Procaine Injectable Suspension is viscous and opaque. Penicillin G Procaine is an equimolecular compound of procaine and penicillin G, administered intramuscularly as a suspension.

It dissolves slowly at the site of injection, giving a plateau type of blood level at about 4 hours which falls slowly over a period of the next 15 to 20 hours.

Bedside testing for penicillin allergies could save lives

The drug is distributed throughout the body tissues in widely varying amounts. Highest levels are found in the kidneys with lesser amounts in the liver, skin, and intestines. Penicillin G penetrates into all other tissues to a lesser degree with a very small level found in the cerebrospinal fluid. With normal kidney function, the drug is excreted rapidly by tubular excretion.

In neonates and young infants and in individuals with impaired kidney functions, excretion is considerably delayed. Approximately 60 to 90 percent of a dose of parenteral penicillin G is excreted in the urine within 24 to 36 hours. Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable.

Penicillin is not active against penicillinase-producing bacteria, or against organisms resistant to beta-lactams because of alterations in the penicillin-binding proteins. Resistance to penicillin G has not been reported in Streptococcus pyogenes. Penicillin G is also active in vitro against susceptible strains of the following organisms: Neisseria meningitidisCorynebacterium diphtheriaeBacillus anthracisClostridium species, Actinomyces speciesSpirillum minus, Streptobacillus moniliformisListeria monocytogenesLeptospira species and Treponema pallidum.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Penicillin G Procaine and other antibacterial drugs, Penicillin G Procaine should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy.

In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Penicillin G Procaine is indicated in the treatment of moderately severe infections in both adults and pediatric patients due to penicillin-G-susceptible microorganisms that are susceptible to the low and persistent serum levels common to this particular dosage form in the indications listed below.

Therapy should be guided by bacteriological studies including susceptibility tests and by clinical response. The following infections will usually respond to adequate dosages of intramuscular Penicillin G Procaine: Moderately severe to severe infections of the upper respiratory tract, skin and soft-tissue infections, scarlet fever, and erysipelas due to susceptible streptococci Group A-without bacteremia.

Other groups, including Group D enterococcusare resistant. Aqueous penicillin is recommended for streptococcal infections with bacteremia.

benzathine penicillin and procaine penicillin

Moderately severe infections of the respiratory tract due to susceptible pneumococci. NOTE: Severe pneumonia, empyema, bacteremia, pericarditis, meningitis, peritonitis, and arthritis of pneumococcal etiology are better treated with aqueous penicillin G during the acute stage.

Moderately severe infections of the skin and soft tissues due to susceptible staphylococci penicillin G-susceptible. NOTE: Reports indicate an increasing number of strains of staphylococci resistant to penicillin G, emphasizing the need for culture and sensitivity studies in treating suspected staphylococcal infections.Jump to content. You should not use this medication if you are allergic to penicillin. Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceftin, Cefzil, Omnicef, Keflex, and others.

Before using benzathine penicillin and procaine penicillin, tell your doctor if you have asthma or a history of allergies, liver disease, kidney disease, or heart disease.

Do not inject this medication into a vein or life-threatening side effects may result. Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Benzathine penicillin and procaine penicillin will not treat a viral infection such as the common cold or flu. After you have finished your treatment with benzathine penicillin and procaine penicillin, your doctor may want to do tests to make sure your infection has completely cleared up.

Benzathine penicillin and procaine penicillin is an antibiotic that fights bacteria in your body. Benzathine penicillin and procaine penicillin is used to treat many different types of severe infections, including strep and staph infections, diphtheria, meningitis, gonorrhea, and syphilis.

Benzathine penicillin and procaine penicillin is also used to prevent infections of the heart valves in people with certain heart conditions who need to have dental work or surgery. Benzathine penicillin and procaine penicillin may also be used for purposes not listed in this medication guide.

Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceclor, Ceftin, Duricef, Keflex, Lorabid, Omnicef, Spectracef, and others. FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Benzathine penicillin and procaine penicillin can pass into breast milk and may harm a nursing baby.

Do not use this medication without telling your doctor if you are breast-feeding a baby. Benzathine penicillin and procaine penicillin is injected into a muscle. A healthcare provider will give you this injection.Benzathine penicillin and procaine penicillin is an antibiotic that fights bacteria in your body.

Benzathine penicillin and procaine penicillin is used to treat many different types of severe infections, including strep and staph infections, diphtheria, meningitis, gonorrhea, and syphilis. Benzathine penicillin and procaine penicillin is also used to prevent infections of the heart valves in people with certain heart conditions who need to have dental work or surgery.

Benzathine penicillin and procaine penicillin may also be used for purposes not listed in this medication guide. You should not use this medication if you are allergic to penicillin. Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceftin, Cefzil, Omnicef, Keflex, and others. Before using benzathine penicillin and procaine penicillin, tell your doctor if you have asthma or a history of allergies, liver disease, kidney disease, or heart disease.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Benzathine penicillin and procaine penicillin will not treat a viral infection such as the common cold or flu. After you have finished your treatment with benzathine penicillin and procaine penicillin, your doctor may want to do tests to make sure your infection has completely cleared up.

Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceclor, Ceftin, Duricef, Keflex, Lorabid, Omnicef, Spectracef, and others. FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Benzathine penicillin and procaine penicillin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. This is not a complete list of side effects and others may occur.

Call your doctor for medical advice about side effects. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking this medication and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

This list is not complete and other drugs may interact with benzathine penicillin and procaine penicillin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Benzathine penicillin and procaine penicillin is injected into a muscle. A healthcare provider will give you this injection. You may be shown how to use injections at home.

Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes. Benzathine penicillin and procaine penicillin must be injected slowly into a muscle of the buttock or upper thigh. Benzathine penicillin and procaine penicillin is sometimes given only once or only for a few days until your symptoms clear up.

Be sure to have all injections your doctor has prescribed.

Benzathine Penicillin-Procaine Penicillin

Your symptoms may get better before the infection is completely cleared. Use a disposable needle only once. Throw away used needles in a puncture-proof container ask your pharmacist where you can get one and how to dispose of it.Procaine penicillin is used to treat many different types of infections caused by bacteria, including syphilis a sexually transmitted disease. You should not use this medication if you are allergic to penicillin. Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceftin, Cefzil, Omnicef, Keflex, and others.

Before using procaine penicillin, tell your doctor if you have asthma or a history of allergies, or kidney disease. Use this medication for the full prescribed length of time.

Procaine benzylpenicillin

Call your doctor if your infection does not improve, or if it gets worse while using procaine penicillin. Tell your doctor about all other medications you use, especially gout medication, a blood thinner, a diuretic, a tetracycline antibiotic, or a non-steroidal anti-inflammatory drug NSAID. Procaine penicillin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control such as a condom, diaphragm, spermicide to prevent pregnancy while using procaine penicillin.

Hormonal forms of contraception such as birth control pills, injections, implants, skin patches, and vaginal rings may not be effective enough to prevent pregnancy during your treatment.

Procaine penicillin

After you have finished your treatment with procaine penicillin, your doctor may want to do tests to make sure your infection has completely cleared up. Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceclor, Ceftin, Duricef, Keflex, Lorabid, Omnicef, Spectracef, and others.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use procaine penicillin:.

FDA pregnancy category B. Procaine penicillin is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Procaine penicillin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, stop using this medication and call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to. This list is not complete and there may be other drugs that can interact with procaine penicillin.

Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.